Genetic variation determines response to anti-diabetic drug
In the first study of its kind, Penn researchers have shown how an anti-diabetic drug can have variable effects depending on small natural differences in DNA sequence between individuals. Mitchell...
View ArticleA metabolic master switch underlying human obesity
Obesity is one of the biggest public health challenges of the 21st century. Affecting more than 500 million people worldwide, obesity costs at least $200 billion each year in the United States alone,...
View ArticleTall and slim: They go together, genetic study shows
University of Queensland scientists have found a genetic basis for height and body mass differences between European populations.
View ArticleDiscovery of genetic differences between relapsing/non-relapsing breast cancers
Although most patients with breast cancer are cured after treatment, in about one in five the cancer will recur, returning either to the same place as the original tumour or spreading to other parts of...
View ArticleCould there be a 'quit-smoking' gene?
(HealthDay)—Some smokers have much more difficulty kicking the habit than others. Now, a new review of prior research identifies a potential culprit: genes.
View ArticleLife history effects on the molecular clock of autosomes and sex chromosomes
Evolutionary geneticists date events using the number of mutations that have accumulated since they occurred. For instance, they date the spilt time between humans and chimps by dividing the number of...
View ArticleStudy uncovers genetic differences for kidney cancer that may contribute to...
A University of North Carolina Lineberger Comprehensive Cancer Center-led study has identified genetic differences in tumors of African-Americans with the most common type of kidney cancer compared...
View ArticleResearchers discover genetic causes of higher melanoma risk in men
A study led by researchers at Universitat Jaume I de Castellón has identified one of the genetic causes underlying the higher rate of melanoma in men. The results have been published in Biology of Sex...
View ArticleGenes are not destiny: Environment and education still matter when it comes...
Recent research has suggested that academic performance, reading ability and IQ have a genetic basis. This reinforces the popular notion that intelligence and related cognitive capacities are somehow...
View ArticleHow baby's genes influence birth weight and later life disease
New research finds genetic differences that help to explain why some babies are born bigger or smaller than others. It also reveals how genetic differences provide an important link between an...
View ArticlePredicting diabetes risk from birth weight
Do you know how much you weighed when you were born? From that first weigh-in moments after birth, it's possible to predict your future adult health. And when it comes to disease risk in later life,...
View ArticleStrain-level profiling yields new insights into mother-infant microbiomes
Direct microbial sequencing of environmental samples, such as from ocean water, hospital surfaces, and the human gut, have illuminated the vast number of microbes present in our world. However, a...
View ArticleLandmark project shows heart disease and arthritis risk raised by genetic...
Today in Cell and associated journals, 24 research studies from the landmark BLUEPRINT project and IHEC consortia reveal how variation in blood cells' characteristics and numbers can affect a person's...
View ArticleGenetic differences in amino acid metabolism are linked to a higher risk of...
A study published today in the journal PLOS Medicine has identified the five genetic variants associated with higher levels of the branched-chain amino acids isoleucine, leucine and valine. The...
View ArticleGenetic risk factors for autism, MS and other diseases differ between the sexes
A pair of studies by researchers at UC San Francisco suggest that genetic variants that have distinct effects on physical traits such as height, weight, body mass, and body shape in men versus women...
View ArticleStudy: Impact of genetics on human height is not increasing
The relative impact of genetics on height does not increase with improvements to the standard of living. These are the findings of an international research group which analysed the impact of genetic...
View ArticleIndividualizing health care one byte at a time
Genetic diagnosis of disease and personalization of treatment have the potential to dramatically improve strategies for diagnosis and therapy. Around 80% or rare diseases are thought to have a genetic...
View ArticleSequencing prostate tumors from African-American men reveals a novel tumor...
African-American men develop prostate cancer more often than other men, and it tends to be more deadly for this population. Some of the differences seem to be due to socioeconomic factors, but...
View ArticleBrain anatomy differs in people with 22q genetic risk for schizophrenia, autism
A UCLA study characterizes, for the first time, brain differences between people with a specific genetic risk for schizophrenia and those at risk for autism, and the findings could help explain the...
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